Thomas M. Hyde

Latest

• Integrating gene expression and imaging data across Visium capture areas with visiumStitched
• A data-driven single-cell and spatial transcriptomic map of the human prefrontal cortex
• Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood
• Analysis of gene expression in the postmortem brain of neurotypical Black Americans reveals contributions of genetic ancestry.
• Transcriptomic analysis of the human habenula in schizophrenia
• Benchmark of cellular deconvolution methods using a multi-assay reference dataset from postmortem human prefrontal cortex
• The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics
• Spatiotemporal analysis of gene expression in the human dentate gyrus reveals age-associated changes in cellular maturation and neuroinflammation
• VistoSeg: Processing utilities for high-resolution images for spatially resolved transcriptomics data
• Comparison of gene expression in living and postmortem human brain
• Influence of Alzheimer's Disease Related Neuropathology on Local Microenvironment Gene Expression in the Human Inferior Temporal Cortex
• Genetics and Brain Transcriptomics of Completed Suicide
• Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain
• Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk
• Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex
• Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation