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    <title>AD | L. Collado-Torres</title>
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      <title>AD</title>
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      <title>APOE E4 Alzheimer’s Risk Converges on an Oligodendrocyte Subtype in the Human Entorhinal Cortex</title>
      <link>https://lcolladotor.github.io/publication/preprint_lff_erc/</link>
      <pubDate>Thu, 20 Nov 2025 00:00:00 +0000</pubDate>
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      <description>&lt;blockquote class=&#34;bluesky-embed&#34; data-bluesky-uri=&#34;at://did:plc:kfflbco44d6dfcs7gatyeve4/app.bsky.feed.post/3m7pkckfzrc2d&#34; data-bluesky-cid=&#34;bafyreibbwe4tzax3gw2nzhbm4kofb37fi2vju5cfxtkdtphfkqfcdp2hc4&#34; data-bluesky-embed-color-mode=&#34;system&#34;&gt;&lt;p lang=&#34;en&#34;&gt;Excited to share our latest preprint from @lieberinstitute.bsky.social spatial + single-cell RNA-seq map the ERC &amp;amp; explore how AD risk shapes gene expression doi.org/10.1101/2025...
Our major finding: “APOE E4 Alzheimer’s Risk Converges on an Oligodendrocyte Subtype in the Human Entorhinal Cortex”&lt;br&gt;&lt;br&gt;&lt;a href=&#34;https://bsky.app/profile/did:plc:kfflbco44d6dfcs7gatyeve4/post/3m7pkckfzrc2d?ref_src=embed&#34;&gt;[image or embed]&lt;/a&gt;&lt;/p&gt;&amp;mdash; Louise Huuki-Myers (&lt;a href=&#34;https://bsky.app/profile/did:plc:kfflbco44d6dfcs7gatyeve4?ref_src=embed&#34;&gt;@lahuuki.bsky.social&lt;/a&gt;) &lt;a href=&#34;https://bsky.app/profile/did:plc:kfflbco44d6dfcs7gatyeve4/post/3m7pkckfzrc2d?ref_src=embed&#34;&gt;December 11, 2025 at 7:13 AM&lt;/a&gt;&lt;/blockquote&gt;&lt;script async src=&#34;https://embed.bsky.app/static/embed.js&#34; charset=&#34;utf-8&#34;&gt;&lt;/script&gt;
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      <title>Impact of Alzheimer’s disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus</title>
      <link>https://lcolladotor.github.io/publication/preprint_lff_lc/</link>
      <pubDate>Fri, 31 Oct 2025 00:00:00 +0000</pubDate>
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      <description>&lt;blockquote class=&#34;bluesky-embed&#34; data-bluesky-uri=&#34;at://did:plc:vhtzwljkdzgy5fkuaqgitc6e/app.bsky.feed.post/3m4isvuqabm2v&#34; data-bluesky-cid=&#34;bafyreigdbmnlonsi3i5uyk2w5ycqvqhgixukoxtzaorwdqwm7wzb63dcvm&#34; data-bluesky-embed-color-mode=&#34;system&#34;&gt;&lt;p lang=&#34;en&#34;&gt;Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
&lt;p&gt;&lt;a href=&#34;https://www.biorxiv.org/content/10.1&#34; target=&#34;_blank&#34; rel=&#34;noopener&#34;&gt;www.biorxiv.org/content/10.1&lt;/a&gt;&amp;hellip;&lt;br&gt;&lt;br&gt;&lt;a href=&#34;https://bsky.app/profile/did:plc:vhtzwljkdzgy5fkuaqgitc6e/post/3m4isvuqabm2v?ref_src=embed&#34;&gt;[image or embed]&lt;/a&gt;&lt;/p&gt;— Bernie Mulvey (&lt;a href=&#34;https://bsky.app/profile/did:plc:vhtzwljkdzgy5fkuaqgitc6e?ref_src=embed&#34;&gt;@berniejmulvey.bsky.social&lt;/a&gt;) &lt;a href=&#34;https://bsky.app/profile/did:plc:vhtzwljkdzgy5fkuaqgitc6e/post/3m4isvuqabm2v?ref_src=embed&#34;&gt;October 31, 2025 at 11:42 AM&lt;/a&gt;&lt;/blockquote&gt;&lt;script async src=&#34;https://embed.bsky.app/static/embed.js&#34; charset=&#34;utf-8&#34;&gt;&lt;/script&gt;&lt;/p&gt;
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      <title>Influence of Alzheimer&#39;s Disease Related Neuropathology on Local Microenvironment Gene Expression in the Human Inferior Temporal Cortex</title>
      <link>https://lcolladotor.github.io/publication/2023_10_visium_spg_ad/</link>
      <pubDate>Mon, 16 Oct 2023 00:00:00 +0000</pubDate>
      <guid>https://lcolladotor.github.io/publication/2023_10_visium_spg_ad/</guid>
      <description>&lt;blockquote class=&#34;twitter-tweet&#34;&gt;&lt;p lang=&#34;en&#34; dir=&#34;ltr&#34;&gt;After 10+ years of research, my FIRST 1st-author paper &amp;amp; &lt;a href=&#34;https://x.com/biorxivpreprint?ref_src=twsrc%5Etfw&#34;&gt;@biorxivpreprint&lt;/a&gt; is finally OUT🥹I delved deep into the human inferior temporal cortex🧠in &lt;a href=&#34;https://x.com/hashtag/Alzheimersdisease?src=hash&amp;amp;ref_src=twsrc%5Etfw&#34;&gt;#Alzheimersdisease&lt;/a&gt;, using &lt;a href=&#34;https://x.com/hashtag/VisiumSPG?src=hash&amp;amp;ref_src=twsrc%5Etfw&#34;&gt;#VisiumSPG&lt;/a&gt; &lt;a href=&#34;https://x.com/hashtag/VectraPolaris?src=hash&amp;amp;ref_src=twsrc%5Etfw&#34;&gt;#VectraPolaris&lt;/a&gt; &lt;a href=&#34;https://x.com/hashtag/RNAscope?src=hash&amp;amp;ref_src=twsrc%5Etfw&#34;&gt;#RNAscope&lt;/a&gt; &amp;amp; &lt;a href=&#34;https://x.com/hashtag/HALO?src=hash&amp;amp;ref_src=twsrc%5Etfw&#34;&gt;#HALO&lt;/a&gt; &lt;a href=&#34;https://x.com/Indica_Labs?ref_src=twsrc%5Etfw&#34;&gt;@Indica_Labs&lt;/a&gt;. Check out our📜at &lt;a href=&#34;https://t.co/QQEy1ZWc1V&#34;&gt;https://t.co/QQEy1ZWc1V&lt;/a&gt;🔥 &lt;a href=&#34;https://t.co/dBZNzL1S96&#34;&gt;pic.twitter.com/dBZNzL1S96&lt;/a&gt;&lt;/p&gt;&amp;mdash; Sang Ho (Sangho) Kwon (@sanghokwon17) &lt;a href=&#34;https://x.com/sanghokwon17/status/1650589385379962881?ref_src=twsrc%5Etfw&#34;&gt;April 24, 2023&lt;/a&gt;&lt;/blockquote&gt;
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