Joo Heon Shin

Latest

• Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood
• Analysis of gene expression in the postmortem brain of neurotypical Black Americans reveals contributions of genetic ancestry.
• Sex affects transcriptional associations with schizophrenia across the dorsolateral prefrontal cortex, hippocampus, and caudate nucleus
• Transcriptomic analysis of the human habenula in schizophrenia
• TrkB-dependent regulation of molecular signaling across septal cell types
• Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes
• Genetics and Brain Transcriptomics of Completed Suicide
• SynGAP isoforms differentially regulate synaptic plasticity and dendritic development
• Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk
• Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs
• Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation
• Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer's disease