L. Collado-Torres
L. Collado-Torres
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An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus
In the human brain, the dorsal anterior cingulate cortex (dACC) plays key roles in various components of cognitive control, and is …
Kinnary Shah
,
Michael S. Totty
,
Svitlana V. Bach
,
Madeline R. Valentine
,
Atharv Chandra
,
Heena R. Divecha
,
Ryan A. Miller
,
Sang Ho Kwon
,
Anthony D. Ramnauth
,
Madhavi Tippani
,
Sanjana Tyagi
,
Joel E. Kleinman
,
Leonardo Collado-Torres
,
Shizhong Han
,
Thomas M. Hyde
,
Stephanie C. Page
,
Kristen R. Maynard
,
Stephanie C. Hicks †
,
Keri Martinowich †
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DOI
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BDNF-DT and BDNF-AS-DT: Novel Genes in the BDNF locus
Divergent transcription from bidirectional promoters is frequently observed in eukaryotic genomes, but the biological relevance of …
Svitlana V. Bach __*__
,
Giovanna Punzi __*__
,
Nuri E. Smith
,
Sreya Mukherjee
,
Joo Heon Shin
,
Qiang Chen
,
Geo Pertea
,
Leonardo Collado-Torres
,
Kristen R. Maynard
,
Stephanie C. Page
,
Joel E. Kleinman
,
Thomas M. Hyde
,
Daniel R. Weinberger
,
Keri Martinowich †
,
Gianluca Ursini †
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DOI
Preprint
Molecular impact of nicotine and smoking exposure on the developing and adult mouse brain
Maternal smoking during pregnancy (MSDP) is associated with significant cognitive and behavioral effects on offspring. While …
Daianna Gonzalez-Padilla
,
Nicholas J. Eagles
,
Marisol Cano
,
Andrew E. Jaffe
,
Kristen R. Maynard
,
Dana B. Hancock
,
James T. Handa
,
Keri Martinowich
,
Leonardo Collado-Torres
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DOI
Preprint
Code
Bioconductor
Network nature of ligand-receptor interactions underlies disease comorbidity in the brain
Neurodegenerative disorders have overlapping symptoms and have high comorbidity rates, but this is not reflected in overlaps of risk …
Melissa Grant-Peters
,
Aine Fairbrother-Browne
,
Amy Hicks
,
Boyi Guo
,
Regina H. Reynolds
,
Louise A. Huuki-Myers
,
Nicholas J. Eagles
,
Jonathan Brenton
,
Sonia Garcia Ruiz
,
Nicholas Wood
,
Sonia Gandhi
,
Kristen Maynard
,
Leonardo Collado-Torres
,
Mina Ryten
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DOI
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Transcriptomic analysis of the human habenula in schizophrenia
Pathophysiology of many neuropsychiatric disorders, including schizophrenia (SCZD), is linked to habenula (Hb) function. While …
Ege A. Yalcinbas __*__
,
Bukola Ajanaku __*__
,
Erik D. Nelson
,
Renee Garcia-Flores
,
Nicholas J. Eagles
,
Kelsey D. Montgomery
,
Joshua M. Stolz
,
Joshua Wu
,
Heena R. Divecha
,
Atharv Chandra
,
Rahul A. Bharadwaj
,
Svitlana Bach
,
Anandita Rajpurohit
,
Ran Tao
,
Geo Pertea
,
Joo Heon Shin
,
Joel E. Kleinman
,
Thomas M. Hyde
,
Daniel R. Weinberger
,
Louise A. Huuki-Myers
,
Leonardo Collado-Torres
,
Kristen R. Maynard †
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Project
DOI
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Comparison of gene expression in living and postmortem human brain
Molecular mechanisms of neuropsychiatric disorders are challenging to study in human brain. For decades, the preferred model has been …
Leonardo Collado-Torres
,
Lambertus Klei
,
Chunyu Liu
,
Joel E. Kleinman
,
Thomas M. Hyde
,
Daniel H. Geschwind
,
Michael J. Gandal
,
Bernie Devlin
,
Daniel R. Weinberger
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DOI
Preprint
Code
Detection of pathogenic splicing events from RNA-sequencing data using dasper
Although next-generation sequencing technologies have accelerated the discovery of novel gene-to-disease associations, many patients …
David Zhang
,
Regina H. Reynolds
,
Sonia Garcia Ruiz
,
Emil K Gustavsson
,
Sid Sethi
,
Sara Aguti
,
Ines A. Barbosa
,
Jack J. Collier
,
Henry Houlden
,
Robert McFarland
,
Francesco Muntoni
,
Monika Oláhová
,
Joanna Poulton
,
Michael Simpson
,
Robert D.S. Pitceathly
,
Robert W. Taylor
,
Haiyan Zhou
,
Charu Deshpande
,
Juan A. Botia
,
Leonardo Collado-Torres
,
Mina Ryten
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Source Document
DOI
recount-brain: a curated repository of human brain RNA-seq datasets metadata
The usability of publicly-available gene expression data is often limited by the availability of high-quality, standardized biological …
Ashkaun Razmara
,
Ellis SE
,
Sokolowski DJ
,
Davis S
,
Wilson MD
,
Leek JT
,
Jaffe AE
,
[__L Collado-Torres__](/authors/admin) †
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Poster
DOI
RNA-seq transcript quantification from reduced-representation data in recount2
More than 70,000 short-read RNA-sequencing samples are publicly available through the recount2 project, a curated database of summary …
Fu J
,
Kammers K
,
Nellore A
,
Leonardo Collado-Torres
,
Leek JT
,
Taub MA
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