derfinder: Annotation-agnostic differential expression analysis of RNA-seq data at base-pair resolution via the DER Finder approach

This package provides functions for annotation-agnostic differential expression analysis of RNA-seq data. Two implementations of the DER Finder approach are included in this package: (1) single base-level F-statistics and (2) DER identification at the expressed regions-level. The DER Finder approach can also be used to identify differentially bounded ChIP-seq peaks.

See also

Useful links:

• https://github.com/lcolladotor/derfinder

• Report bugs at https://support.bioconductor.org/t/derfinder/

Author

Maintainer: Leonardo Collado-Torres lcolladotor@gmail.com (ORCID)

Authors:

• Andrew E. Jaffe andrew.jaffe@libd.org (ORCID)

• Jeffrey T. Leek jtleek@gmail.com (ORCID) [thesis advisor]

Other contributors:

• Alyssa C. Frazee alyssa.frazee@gmail.com [contributor]