L. Collado-Torres
L. Collado-Torres
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deconvolution
Benchmarking cell type deconvolution methods with human brain data
I enjoyed presenting our deconvolution benchmark study for the #SingleCell genomics webinar series for Latin America organized with @eventsWCS support 📜 https://t.co/hUW5cz3ubm led by @lahuuki & https://t.co/jXHOzyOrf8 Slides by @lahuuki + minor updateshttps://t.
Leonardo Collado-Torres
Last updated on Sun, Nov 10, 2024
Project
Slides
lute: estimating the cell composition of heterogeneous tissue with varying cell sizes using gene expression
Relative cell type fraction estimates in bulk RNA-sequencing data are important to control for cell composition differences across …
Sean K. Maden
,
Louise A. Huuki-Myers
,
Sang Ho Kwon
,
Leonardo Collado-Torres
,
Kristen R. Maynard
,
Stephanie C. Hicks
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Bioconductor
Benchmark of cellular deconvolution methods using a multi-assay reference dataset from postmortem human prefrontal cortex
Background
Cellular deconvolution of bulk RNA-sequencing (RNA-seq) data using single cell or nuclei RNA-seq (sc/snRNA-seq) reference …
Louise A. Huuki-Myers
,
Kelsey D. Montgomery __*__
,
Sang Ho Kwon
,
Sophia Cinquemani
,
Nicholas J. Eagles
,
Daianna Gonzalez-Padilla
,
Sean K. Maden
,
Joel E. Kleinman
,
Thomas M. Hyde
,
Stephanie C. Hicks
,
Kristen R. Maynard †
,
Leonardo Collado-Torres
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Project
DOI
Preprint
Code
Bioconductor
Challenges and opportunities to computationally deconvolve heterogeneous tissue with varying cell sizes using single-cell RNA-sequencing datasets
Deconvolution of cell mixtures in “bulk” transcriptomic samples from homogenate human tissue is important for understanding disease …
Sean K. Maden
,
Sang Ho Kown
,
Louise A. Huuki-Myers
,
Leonardo Collado-Torres
,
Stephanie C. Hicks †
,
Kristen R. Maynard †
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Preprint
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R Package
Data-driven identification of total RNA expression genes for estimation of RNA abundance in heterogeneous cell types highlighted in brain tissue
We define and identify a new class of control genes for next-generation sequencing called total RNA expression genes (TREGs), which …
Louise A. Huuki-Myers
,
Kelsey D. Montgomery
,
Sang Ho Kwon
,
Stephanie C. Page
,
Stephanie C. Hicks
,
Kristen R. Maynard †
,
Leonardo Collado-Torres †
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DOI
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Documentation
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Source
Lessons from spatially-resolved transcriptomics of postmortem human brain data projects
Join me and others for free** at #FOGBoston October 4-5 2023 https://t.co/5BGgkBKZuN ⚾️🧦🎉 I'll talk about our work at @LieberInstitute @jhubiostat on spatially-resolved transcriptomics using #Visium #VisiumSPG by @10xGenomics 🎫 https://t.
Leonardo Collado-Torres
Last updated on Mon, Feb 26, 2024
Project
Project
Slides
Studying the human prefrontal cortex transcriptome at different resolutions
¡Seguimos! #LCG20 Simposio # 5: Spatial Transcriptomics https://t.co/I8J3PXRqAT @ccg_unam @ibt_unam @unammorelos @lcolladotor @daniela_oaks @roramirezf94 #EnVivo pic.twitter.com/mcrdyTABqa — LCG UNAM (@lcgunam) August 31, 2023
Leonardo Collado-Torres
Last updated on Mon, Feb 26, 2024
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Project
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Slides
Lessons from working on the edge of human brain transcriptomics with spatially-resolved transcriptomics and deconvolution
Invited seminar by Sebastian Guelfi
Leonardo Collado-Torres
Last updated on Mon, Feb 26, 2024
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Project
Slides
Lessons from working on the edge of human brain transcriptomics with spatially-resolved transcriptomics and deconvolution
Invited seminar by Sonia Gandhi
Leonardo Collado-Torres
Last updated on Tue, Jun 20, 2023
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Project
Slides
Navigating human brain gene expression measurements at different resolutions to study psychiatric disorders
Invited seminar by Mina Ryten
Leonardo Collado-Torres
Last updated on Tue, Jun 20, 2023
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