L. Collado-Torres
L. Collado-Torres
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Activity-regulated gene expression across cell types of the mouse hippocampus
Activity-regulated gene (ARG) expression patterns in the hippocampus (HPC) regulate synaptic plasticity, learning, and memory, and are …
Erik D. Nelson
,
Kristen R. Maynard
,
Kyndall R. Nicholas
,
Matthew N. Tran
,
Heena R. Divecha
,
Leonardo Collado-Torres
,
Stephanie C. Hicks †
,
Keri Martinowich †
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DOI
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Code
iSEE app
IntroVerse: a comprehensive database of introns across human tissues
Dysregulation of RNA splicing contributes to both rare and complex diseases. RNA-sequencing data from human tissues has shown that this …
Sonia Garcia Ruiz
,
Emil K Gustavsson
,
David Zhang
,
Regina H Reynolds
,
Zhongbo Chen
,
Aine Fairbrother-Browne
,
Ana Luisa Gil-Martínez
,
Juan A Botia
,
Leonardo Collado-Torres
,
Mina Ryten
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DOI
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IntroVerse
Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes
Most studies of gene expression in the brains of individuals with schizophrenia have focused on cortical regions, but subcortical …
Kynon JM Benjamin
,
Qiang Chen
,
Andrew E Jaffe
,
Joshua M. Stolz
,
Leonardo Collado-Torres
,
Louise A. Huuki-Myers
,
Emily E Burke
,
Ria Arora
,
Arthur S Feltrin
,
André Rocha Barbosa
,
Eugenia Radulescu
,
Giulio Pergola
,
Joo Heon Shin
,
William S Ulrich
,
Amy Deep-Soboslay
,
Ran Tao
,
The BrainSeq Consortium
,
Thomas M Hyde
,
Joel E Kleinman
,
Jennifer A Erwin †
,
Daniel R Weinberger †
,
Apuã CM Paquola †
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PDF
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DOI
Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review
Following the recent review by Merikangas et al. summarizing differential gene expression in schizophrenia, we wanted to provide …
Gabriel E. Hoffman †
,
Andrew E. Jaffe †
,
Michael J. Gandal †
,
Leonardo Collado-Torres
,
Solveig K. Sieberts
,
Bernie Devlin
,
Daniel H. Geschwind
,
Daniel R. Weinberger
,
Panos Roussos
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Project
DOI
spatialLIBD: an R/Bioconductor package to visualize spatially-resolved transcriptomics data
Background
. Spatially-resolved transcriptomics has now enabled the quantification of high-throughput and transcriptome-wide gene …
Brenda Pardo
,
Abby Spangler
,
Lukas M. Weber
,
Stephanie C. Hicks
,
Andrew E. Jaffe
,
Keri Martinowich
,
Kristen R. Maynard
,
Leonardo Collado-Torres
Preprint
PDF
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Slides
Source Document
DOI
SpatialExperiment: infrastructure for spatially resolved transcriptomics data in R using Bioconductor
Summary
SpatialExperiment is a new data infrastructure for storing and accessing spatially resolved transcriptomics data, implemented …
Dario Righelli __*__
,
Lukas M. Weber __*__
,
Helena L. Crowell __*__
,
Brenda Pardo
,
Leonardo Collado-Torres
,
Shila Ghazanfar
,
Aaron T. L. Lun,
,
Stephanie C. Hicks †
,
Davide Risso †
Preprint
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DOI
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways
Recent genetic studies have identified variants associated with bipolar disorder (BD), but it remains unclear how brain gene expression …
Peter P. Zandi
,
Andrew E. Jaffe
,
Fernando S. Goes
,
Emily E. Burke
,
Leonardo Collado-Torres
,
Louise A. Huuki-Myers
,
Arta Seyedian
,
Yian Lin
,
Fayaz Seifuddin
,
Mehdi Pirooznia
,
Christopher A. Ross
,
Joel E. Kleinman
,
Daniel R. Weinberger
,
Thomas M. Hyde †
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Genetics and Brain Transcriptomics of Completed Suicide
Objective: The authors sought to study the transcriptomic and genomic features of completed suicide by parsing the method chosen, to …
Giovanna Punzi
,
Gianluca Ursini
,
Qiang Chen
,
Eugenia Radulescu
,
Ran Tao
,
Louise A. Huuki-Myers
,
Pasquale Di Carlo
,
Leonardo Collado-Torres
,
Joo Heon Shin
,
Roberto Catanesi
,
Andrew E. Jaffe
,
Thomas M. Hyde
,
Joel E. Kleinman
,
Trudy F.C. Mackay
,
Daniel R. Weinberger †
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recount3: summaries and queries for large-scale RNA-seq expression and splicing
We present recount3, a resource consisting of over 750,000 publicly available human and mouse RNA sequencing (RNA-seq) samples …
Christopher Wilks
,
Shijie C. Zheng
,
Feng Yong Chen
,
Rone Charles
,
Brad Solomon
,
Jonathan P. Ling
,
Eddie Luidy Imada
,
David Zhang
,
Lance Joseph
,
Jeffrey T. Leek
,
Andrew E. Jaffe
,
Abhinav Nellore
,
Leonardo Collado-Torres
,
Kasper D. Hansen †
,
Ben Langmead †
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PDF
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Dataset
Project
Source Document
DOI
Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain
Single-cell gene expression technologies are powerful tools to study cell types in the human brain, but efforts have largely focused on …
Matthew N. Tran __*__
,
Kristen R. Maynard __*__
,
Abby Spangler
,
Louise A. Huuki-Myers
,
Kelsey D. Montgomery
,
Vijay Sadashivaiah
,
Madhavi Tippani
,
Brianna K. Barry
,
Dana B. Hancock
,
Stephanie C. Hicks
,
Joel E. Kleinman
,
Thomas M. Hyde
,
Leonardo Collado-Torres
,
Andrew E. Jaffe †
,
Keri Martinowich †
Preprint
PDF
Cite
Code
DOI
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