Selected Publications

recount2 provides a valuable and user-friendly resource of processed RNA-seq datasets to draw additional biological insights from existing public data.
Nature Biotechnology

derfinder analysis using expressed region-level and single base-level approaches provides a compromise between full transcript reconstruction and feature-level analysis. The package is available from Bioconductor.
NAR

Recent Publications

More Publications

Expression of the gene set of HNMT, HRH1, HRH2 and HRH3 was significantly altered between ASD and matched controls, and this finding was replicated with an independent data set.
Translational Psychiatry

recount2 provides a valuable and user-friendly resource of processed RNA-seq datasets to draw additional biological insights from existing public data.
Nature Biotechnology

Using developmental, genetic, and illness-based RNA sequencing expression analysis, we characterized the human brain transcriptome around 108 loci that confer risk for schizophrenia and found enrichment for developmentally regulated genes with novel examples of shifting isoform usage across pre- and post-natal life.
bioRxiv

We found 56,861 junctions (18.6%) in at least 1000 samples that were not annotated out of 21,504 samples, and their expression associated with tissue type. We compiled junction data into a resource called intropolis available at http://intropolis.rail.bio.
Genome Biology

derfinder analysis using expressed region-level and single base-level approaches provides a compromise between full transcript reconstruction and feature-level analysis. The package is available from Bioconductor.
NAR

Recent Posts

More Posts

As you might know by now, the latest R version was recently released (R 3.4.0). That means that you are highly encouraged to update your R installation. There are several ways to do this some of which are documented in these other blog posts: Tal Galili, 2013, Kris Eberwein, 2015. You would think that it’s just a matter of downloading the latest R installer for your OS, installing it, and continuing your analysis.

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tl;dr Please post your question at the Bioconductor support website https://support.bioconductor.org/ and check the posting guide http://www.bioconductor.org/help/support/posting-guide/. It’s important that you provide reproducible code and information about your R session. Recently I have been getting more questions about several packages I maintain. It’s great to see more interest from users, but at the same time most questions lack the information I need to help the users. I have also gotten most of the questions via email, which is why I am writing this post.

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tl;dr There is a 600 million to 2 billion USD annual market related to crossing the Mexico-US border. Allow temporary work visas (say 3 years) to take over this market and use the money to boost the US Border Patrol to build a wall of eyes, not a physical wall. President Trump of the United States of America, cc President Peña Nieto of the United Mexican States Today, Wednesday January 25th 2017, you are expected to announce your plans about building a wall between the United States and Mexico.

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Have you ever had to explore a table with data? I believe the answer is yes for most people that work at a computer or even just use it for communicating with their friends and family. Tables of data pop up everywhere, for example in personal finance. Websites like Mint.com allow you to download your transactions in a CSV file called transactions.csv. CSV is one of the many formats for storing tables and most likely when you try to open the transactions.

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Over the weekend my brother wanted to figure out his class schedule for the next semester. He is a veterinary medicine and zootechnology student at UNAM. For this upcoming semester there is a set of classes he has to take and each has 8 or so instructor options. The website where he finds the class times lists about 8 pre-constructed class schedules. So he normally finds one he likes quite a bit, and then manually starts checking if he can change X instructor for Y for a given class.

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Curriculum vitae

Download my cv or view it at GitHub.

Teaching

LIBD

2016

  1. Biostatistics and Stata instructor at a workshop for Kandahar University Faculty, organized by Johns Hopkins University.
  2. Invited instructor for the Genomeeting 2016 course at INMEGEN, Mexico City, Mexico.

JHBSPH

2015-2016

  1. Teaching assistant and guest lecturer for Introduction to R for Public Health Researchers
  2. Teaching assistant for Statistical Methods in Public Health I (140.621)
  3. Lead teaching assistant for Statistical Methods in Public Health II (140.622).
  4. Teaching assistant for the MPH capstone project.

2014-2015

  1. Lead teaching assistant for Statistical Methods in Public Health I (140.621) and II (140.622).
  2. Teaching assistant for the MPH capstone project.

2013-2014

  1. Teaching assistant for Statistical Methods in Public Health I (140.621) and II (140.622).
  2. Teaching assistant for the MPH capstone project. Developed a shiny application that allows students to sign up for a TA session (code) and wrote a report of the number of TA sessions available here.

2012-2013

  1. Teaching assistant for Statistical Methods in Public Health I (140.621), II (140.622), III (140.623), and IV (140.624) courses.

UNAM

PDCB

While working at Winter Genomics I taught two courses for students of the Biomedical Sciences PhD Program (PDCB) from the National Autonomous University of Mexico (UNAM).

  1. Analysis of High-Throughput Sequencing data with Bioconductor Aug-Dec 2010.
  2. Introduction to R and Biostatistics (along with two other teachers).

IBT

While I was at the Institute of Biotechnology (UNAM) working with the Winter Genomics crew I organized two courses. One was a series of various bioinformatics and biology mini-courses and another one involved members of different institutions.

  1. Introduction to R for bench biologists Oct-Nov 2009. This mini-course has quite a bit of material on learning how to make plots with R.
  2. Métodos Estadísticos y Analíticos de Datos Genómicos (Statistical Methods and Analysis of Genomic Data) Jan 2010. This one week course had lectures about Perl, using a Cluster, high-throughput technologies, R and Bioconductor, C, and biology overviews.

LCG

I taught three courses during my undergrad stage at the Undergraduate Program on Genomic Sciences (LCG). Each of these courses has its own website organizing the material. These are:

  1. Intensive course on R/Bioconductor Oct-Nov 2008 (backup)
  2. Principles of Statistics Feb-June 2009 (backup)
  3. Seminar III: R/Bioconductor Aug-Dec 2009 (backup)

Contact

If you have questions about the Bioconductor packages I maintain, please read this post. If you send me an email, I’ll simply refer you to the same post.